Genes of Interest: AMPD1, IL6, ACTN3,NOS3, ACE, VEGFA, AGT, PPARA, TRHR, LEPR, IGF2, COMT
The genes AMPD1, IL-6, ACTN3, NOS3, ACE, VEGFA, AGT, PPARA, TRHR, LEPR, INS-IGF2, and COMT can play a role in the benefits of creatine supplementation. Creatine is a naturally occurring substance found in the body, but it can also be taken as a supplement to help improve athletic performance and increase muscle mass.
AMPD1 helps regulate the production of adenosine triphosphate (ATP), which is the energy source for muscle contractions. IL-6 is involved in inflammation and muscle repair processes. ACTN3 is associated with muscle fiber type, which can impact athletic performance. NOS3 helps regulate blood flow and oxygen delivery to the muscles.
ACE, VEGFA, AGT, and PPARA all play a role in blood flow and cardiovascular health. TRHR and LEPR help regulate metabolism and appetite. INS-IGF2 is involved in insulin regulation and the growth of muscle tissue. COMT is involved in the metabolism of neurotransmitters, including dopamine and adrenaline, which can impact athletic performance.
Overall, these genes can impact the benefits of creatine supplementation by influencing muscle function, metabolism, and cardiovascular health. However, more research is needed to fully understand the complex interactions between these genes and creatine supplementation.