Genes of Interest: FAM9B, PDE7B, SHBG, HSD17B3
Testosterone is a male sex hormone that plays a crucial role in several physiological processes, including muscle growth, bone density, and sperm production. Natural testosterone levels can be influenced by several genetic factors, including variations in genes such as FAM9B, PDE7B, SHBG, and HSD17B3.
FAM9B is a gene that regulates the growth and division of cells. One study found that mutations in FAM9B can lead to decreased testosterone levels in men.
PDE7B is a gene that helps regulate the activity of testosterone. Mutations in PDE7B can lead to decreased testosterone levels and other hormonal imbalances.
SHBG (Sex Hormone Binding Globulin) is a protein that binds to testosterone in the blood, making it inactive. Variations in the SHBG gene can affect how much testosterone is available for use in the body.
HSD17B3 is an enzyme that plays a role in the production of testosterone. Mutations in the HSD17B3 gene have been linked to decreased testosterone levels and other hormonal imbalances.
It's important to note that genetics is just one factor that can affect testosterone levels. Other factors such as diet, exercise, and overall health also play a role. Additionally, it's important to talk to a doctor before making any changes to your health regimen based on genetic information.